Job Information
Amgen Principal Scientist in South San Francisco, California
HOW MIGHT YOU DEFY IMAGINATION?
You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Principal Scientist
Live
What you will do
Let’s do this. Let’s change the world. In this vital role you will lead the design and execution of complex research projects, and oversee a team of scientists. Together you will contribute to the development of the company's research strategies and play a key role in the interpretation and communication of research results.
Lead immuno-oncology discovery research projects (as a Biology or Project Team Lead) and develop novel immuno-oncology therapeutics.
Independently design experimental strategy, execute laboratory-based experiments, analyze data, and communicate and present in team and departmental meetings.
Stay up to date with relevant literature and incorporate findings into program strategies as well as experimental design and implementation.
Publish experimental findings in top-tier journals and present at leading scientific conferences.
Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is someone with these qualifications.
Basic Qualifications:
Doctorate degree and 4 years of immunology or oncology experience
Or
Master’s degree and 7 years of immunology or oncology experience
Preferred Qualifications:
Doctorate degree with postdoctoral training and research experience in biopharmaceutical industry in the field of immunology or cancer biology.
Demonstrated expertise in immunology and/or cancer biology as evidenced with publications in high impact journals and/or patents.
Demonstrate independence and creative thinking in leading drug-discovery projects, designing in vitro and in vivo biological studies, as well as the ability to troubleshoot and solve complex problems.
Demonstrate technical expertise in the following areas: multi-color flow cytometry, primary immune cell culture, and genetic engineering (molecular biology).
Hands-on experience with mRNA-transfection-based assays and 3D complex cell-based assays for co-culture of tumor cells, T cells and myeloid cells is highly preferred.
Direct experience with downstream target validation by understanding oncogenic signaling pathways is a plus.
Direct experience with T cell-targeted therapy development (e.g. multi-specific antibodies, cell therapiesor small molecules) is a plus.
Direct experience with various preclinical animal models of cancer, including design of efficacy/PD (pharmacodynamics) endpoints, and/or adoptive T cell transfer is a plus.
Strong interpersonal communication skills, both verbal and written.
Effectively prioritize and implement next steps with efficient time management.
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models, including remote work arrangements, where possible
Apply now
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.