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Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Pharmaceutical Candidate Optimization organization at Bristol Myers Squibb is a dynamic, multi-disciplinary department that works to discover and optimize new drug candidates. We work across all therapeutic areas and all modalities (small molecules, biotherapeutics, gene and cell therapies and other novel modalities), and engage with all other R&D functions to advance new assets in the BMS portfolio. Our integrated, cross-functional teams apply deep expertise in drug metabolism, pharmacokinetics (DMPK), toxicology, pharmaceutics, and bioanalysis to identify and solve issues, discover high quality drug candidates, and enable their clinical development.

Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

The Director, Drug Metabolism and Pharmacokinetics (DMPK) for BMS-San Diego, oversees the research activities of the San Diego based team of 9 scientists and will report to the global head of Discovery DMPK within the Pharmaceutical Candidate Optimization (PCO) department. They will interface with scientists focused on Discovery efforts in San Diego and across BMS research sites. The PCO organization is a multi-disciplinary department whose cross-functional teams apply deep expertise in DMPK, toxicology, pharmaceutics and bioanalysis to identify and solve issues, discover high quality drug candidates and enable their clinical development.

Key Responsibilities

Critical activities of this leader include proven ability to:

• Lead scientific efforts to characterize metabolic fate and pharmacokinetic properties of drug candidates (small molecules, biologics, and novel modalities) to inform and direct lead optimization of drug candidates; proactively identify issues and enable investigative efforts that further enhance optimization of drug candidates

• Work collaboratively with the San Diego-based DMPK team and internal partners to design, plan, execute and interpret DMPK studies. The incumbent is expected to advise on strategies to resolve DMPK issues that arise on programs.

• Work collaboratively with DMPK scientists across BMS discovery sites to enable strategic integration of DMPK research across the discovery portfolio

• Ensure that the DMPK team is current with emerging concepts and technologies so that these tools can be applied as appropriate for issues resolution.

• Work closely and collaboratively with colleagues in other functions of PCO, including discovery toxicology, pharmaceutics and analytical sciences to ensure a coordinated approach to discovery efforts.

• Maintain a strong external presence in the DMPK community through publications and conference presentations.

• Effectively lead, manage and develop DMPK scientists

Basic Qualifications:

Bachelor's Degree and 15+ years of Academic / Industry experience

Or

Master's Degree and 12+ years of Academic / Industry experience

Or

PhD and 8+ years of Academic / Industry experience

And

6+ years of Leadership experience

Preferred Qualification:

• Ph.D. degree in any area of drug disposition, with emphasis on metabolism, pharmacokinetics or biochemical toxicology, with experience in drug discovery and development. Knowledge of computational approaches, including machine learning tools, to advance predictive tools for ADME-related aspects of drug discovery is desired.

• At least 8 years of experience in conducting and leading research efforts in drug metabolism and pharmacokinetics

• At least 6+ years of leadership experience

• Proven track record of problem-solving skills and ability to integrate across disciplines to address issues and identify mitigation strategies.

• Highly effective written and oral communication skills including contributions to the published literature.

• Strong interpersonal skills with evidence for effective management of a dynamic team and commitment to professional development of all personnel.

For California Sites - The starting compensation for this job is a range from $194,000 - $230,000 , plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Company: Bristol-Myers Squibb

Req Number: R1579565

Updated: 2024-04-26 01:25:13.826 UTC

Location: San Diego-CA

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.