System One Services Clinical Scientist in Princeton, New Jersey
Clinical ScientistPrinceton, NJ
Category:Scientific & Clinical
Title: Senior Scientist Immune Profiling
We are seeking a highly motivated and enthusiastic scientist to join our late clinical development team in the Translational Medicine group.
The position will involve the development, validation and execution of high dimensional flow cytometry panels for deep immune phenotyping of tumor infiltrating lymphocytes as well as peripheral immune cells.
In addition, the candidate will be involved in developing complex in vitro/ex vivo immune & tumor cell culture systems to investigate the mechanism of action of our late stage clinical assets in the immuno oncology space.
PhD with 0-2 years of experience or BS/MS with 3-5 years of experience in Immunology, Cell Biology, Tumor Biology or related field
Knowledge of human immune and tumor biology, with a focus on interactions between tumor and immune cells in the tumor microenvironment
Technical expert in high dimensional flow cytometry, including demonstrated by ability to independently design, validate, execute and analyze novel (12+ colors) panels for deep longitudinal immune profiling
Detailed understanding of cytometers/software on the market
Strong ability to analyze and integrate complex data sets and present conclusions to translational research team
Experience with high dimensional data analysis and dimensionality reduction algorithms is a plus
Hands-on-experience isolating and culturing primary human immune cells, including processing of tumor samples to enrich for tumor infiltrating cells; willingness to work with human derived samples and potentially biohazardous/infectious material
Flexibility to taking on a role in a diverse multifunctional research team, prior experience as part of multidisciplinary team in an academic or industrial environment is a plus
Excellent written and oral presentation skills
Joule, a System One division is a leader in specialized workforce solutions and integrated services. With more than 6,000 employees and roughly 50 offices throughout the U.S. we provide scientific, clinical, engineering, energy, IT, legal and administrative staffing services. For more than 40 years, we have delivered workforce solutions and integrated services to clients nationally.