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WuXi AppTec Technical Operation Group Leader, Peptide & Oligo Process Development in Changzhou, China

Overview

STA Pharmaceutical Co., Ltd., a WuXi AppTec company (WuXi STA), is a global leading small molecule pharmaceutical development and manufacturing capability and technology platform company serving the life science industry, with operations in China and the United States. As a premier Contract Development and Manufacturing Organization (CDMO), STA offers our worldwide partners efficient, flexible and high-quality solutions for small molecule Active Pharmaceutical Ingredients (APIs) and finished dosage forms.

  • A Leading Company of Contract Development and Manufacturing Organization(CDMO)

  • The World’s Largest Process Chemistry Team

  • To learn the most cutting edge technologies in the pharmaceutical development field

  • To work with 200+ global new drug development companies

  • Systemic and Multiple Training Programs(Technical/Soft skills/Management)

  • Diversified Career Development and Promotion Trails

Job Location: Changzhou City, Jiangsu Province

Responsibilities

  • Provides technical support for pilot- and commercial-scale production of intermediates and API that requires the application of innovative manufacturing technologies, especially for Oligo/Peptide SPPS, preparative chromatography (HPLC, IEX, UFDF, etc.), and lyophilization. Technical support are realized in the form of (include but are not limited to):

  • Design, modification and assembly of equipment and set up

  • Selection and evaluation of process technology and methods

  • Development, determination and optimization of process parameters

  • Devise tests before actual production, collect and analyze process data

  • Enabling, execution and troubleshooting of production

  • Serves as the subject matter expert or chief process engineer to communicate with clients and internal stakeholders to understand their technical requirements on API production. Translate such request into well-defined and practicable action items for the production team to implement. Report the production results afterwards, summarize key findings & problems, and suggest solutions for future improvement.

  • Keep track of the status of existing manufacturing technologies that are already applied and identify areas of deficiency. Devise plans, action items and resources for technology consolidation, debottlenecking and continuous improvement.

  • Explore, introduce and develop new technical capabilities and platforms based on project and market need by collaborating with R&D teams or other departments. Formulate long- term technical roadmaps to facilitate business growth and to create new source of revenue for the company.

  • Supervise and mentor a team of subject matter experts and process engineers to ensure all the relevant API production projects are fully supported, and to build up a pipeline of versatile talents to meet the rapid growth in the service of the company.

  • Manages a pool of specialized equipment and a number of laboratories and warehouses for SPPS, preparative chromatography and lyophilization. Adopt measures to maintain well-organized inventory, maximize equipment utilization rate and minimize the maintenance cost.

  • Establish, develop and continuously upgrade the GMP documentation systems, standard operating procedures (SOP), technical working instruction (TWI) of various manufacturing technologies to ensure the production operation are compliant with the GMP policy and to satisfy the highest safety standard.

  • Provides technical trainings and seminars to personnel of other departments to promote the application of new manufacturing technologies, and to resolve any misconception and miscommunication.

Qualifications

  • Master, or more preferably, doctoral degree in chemical engineering, pharmaceutical engineering or other relevant disciplines

  • 3+ years research or industrial experience in pharmaceutical, chemical or other related

  • industries/oversea study research and working experience is definitely an advantage

  • Familiar with Oligo/Peptide API manufacturing process and/or common chemical unit operations

  • Solid knowledge or experience in Oligo/Peptide chemistry, preparative chromatography and /or lyophilization is an advantage

  • Familiarity with GMP operation is preferred

  • Good oral and written communication skill in English and Mandarin is a must

Equal Opportunity Employer Minorities/Women/Veterans/Disabled

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We can recommend jobs specifically for you! An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disabilityAn Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability (https://careers-wuxiapptec.icims.com/connect?back=intro&findajob=1&in_iframe=1&hashed=-435740542)

Job Locations CN-Changzhou

Job ID 2020-7514

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