Johns Hopkins University Sr. Research Specialist in Baltimore, Maryland
The Laboratory of Genetic Neurobiology, part of the Division of Neurobiology in the Department of Psychiatry and Behavioral Sciences, focuses on investigating pathogenic pathways and finding novel therapeutic targets for genetic neurodegenerative and neuropsychiatric diseases, including Huntington’s disease and related disorders, spinocerebellar degenerative disorders, and schizophrenia. We make extensive use of cell and animal models, and employ a variety of molecular and biochemical techniques.
We are seeking a Senior Research Specialist who will make intellectual contribution to the scientific research interests of the lab. In collaboration with PI, make research project decisions that may alter research objectives and direction as well as contribute to writing peer-reviewed manuscripts and grants.
Specific Duties & Responsibilities:
Collaborate with the Principal Investigator to oversee scientific management of the research laboratory.
Manage independent research projects in collaboration with the Principal Investigator and collaborating investigator.
Identify and select best options for scientific strategies and research development based on literature reviews and collaboration with colleagues.
Incorporate new technologies into the laboratory.
Development, validation, and implementation of assays for cell and animal work.
Evaluate options and make decisions regarding the purchase of new laboratory equipment.
Contribute to writing of scientific publications and grant applications, including generating figures.
Act as a resource for laboratory techniques for junior technicians, students, post-doctoral fellows, and Divisional investigators.
Identify problems and propose and implement plan for solutions.
Manage mouse colonies, including care, breeding, tracking with software, genotyping, injections, behavioral testing, and tissue harvesting and preparation.
Cell culture, including standard cell lines, the growth and differentiation of stem cells (iPSCs), and primary culture including dissections.
Perform molecular and biochemical assays on cells and rodent and human tissues. Tasks will include cell transfection, PCR, quantitative PCR, Western blotting, immunohistochemistry and in situ hybridization, and molecular cloning.
Manage daily lab operations, including ordering and managing laboratory supplies, compliance with regulatory requirements, care and maintenance of laboratory equipment, and coordinating among laboratory research projects within and outside of our laboratory group.
Perform miscellaneous related duties as assigned.
Problem Solving Skills:
Identify problem areas and propose and implement plans for solutions.
Draw upon extensive experience and collaborative resources to make decisions about experimental procedures.
Take active role in conjunction with PI, collaborators, post-docs, and advanced students in assessing the objectives and methods of scientific projects.
Exercise authority and intervenes to resolve scientific and administrative issues.
Provide constructive guidance to entry-level and peer lab members in a collegial manner.
Perform constructive self-assessment and solicits feedback from faculty and/or other lab members as appropriate.
Utilize and enhance advanced professional and scientific communication skills.
Keep PI informed of scientific and administrative activities of the lab.
Minimum Qualifications (Mandatory):
Bachelor's degree in biology, chemistry or related field.
4 years experience in a comparable laboratory performing relevant techniques.
Master's degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.
- Master’s degree in Science, Biotechnology.
Special Knowledge, Skills & Abilities :
- Skilled in specialized microscopy, bioinformatics, animal surgery, cell metabolism, etc.
- Sufficient eye-hand coordination for performing experiments using hand-held pipettes.
- Supervision of junior technician and students.
JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
Classified Title: Sr. Research Specialist
Starting Salary Range: $45,195 - $62,225 annually (commensurate with experience)
Employee group: Full Time
Schedule: M-F 8:30 to 5 pm
Exempt Status: Exempt
Location: School of Medicine Campus
Department name: SOM Psy Neurobiology
Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
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